We study how cells sense and respond to their environment by regulating mRNA translation.

Recent News

Nov 1: Our research is supported by a V Scholar Grant from the V Foundation.

Oct 1: Our lab is supported by a grant from The Mathers Foundation.

Aug 16: Our lab is funded by a Maximizing Investigators' Research Award (MIRA R35) from NIH NIGMS.

Jul 14: Our collaboration with the Kranzusch lab on cGAS-like receptor sensing of RNA in Drosophila is published at Nature.

Dec 1: The Lee Lab joins DFCI Cancer Immunology + Virology and HMS Cell Biology.

Nov 13: Our paper describing a new mechanism of translation reprogramming that is critical for the cellular response to metabolic stress is published at Science! Read it here: "A phosphorylation-regulated eIF3d translation switch mediates cellular adaptation to metabolic stress."

Join us!

We are seeking motivated and creative scientists to join our team.

Post-doctoral fellows: Recent Ph.D. graduates with a strong record of publication and training in molecular/cell biology or biochemistry can send a C.V. and contact information for 3 references to amysy_lee [at] dfci.harvard.edu.

Graduate students can join the lab through the BBS and Virology graduate programs at Harvard. Email for information on rotation projects.

Undergraduates: Email with a C.V. and cover letter including research interests.

All content © Amy Lee 2021