We study how cells sense and respond to their environment by regulating mRNA translation.

Recent News

May 07: Congratulations to Sadie on a great senior honors thesis talk and defense, and we are excited for her to head off to join the Harvard Virology PhD program!

May 06: Congratulations to Dr. Becca Fleming on a successful defense talk and examination! Our lab's first PhD graduate!

March 16: Welcome to our BBS rotation student, Manasvi Verma.

Jan 25: Welcome to our Virology rotation student, Gabrielle Law.

Dec 3: The Lee Lab moves into DFCI Smith 5!

Dec 1: The Lee Lab joins DFCI Cancer Immunology + Virology and HMS Cell Biology!

Nov 13: Our paper describing a new mechanism of translation reprogramming that is critical for the cellular response to metabolic stress is published at Science! Read it here: "A phosphorylation-regulated eIF3d translation switch mediates cellular adaptation to metabolic stress."

Join us!

We are seeking motivated and creative scientists to join our team.

Post-doctoral fellows: Recent Ph.D. graduates with a strong record of publication and training in molecular/cell biology or biochemistry, please send a C.V. and contact information for 3 references to amysy_lee [at] dfci.harvard.edu.

Graduate students can join the lab through the BBS and Virology graduate programs at Harvard. Email for information on rotation projects.

Undergraduate students: Email with a CV and a cover letter detailing research interests and prior lab experience.

All content © Amy Lee 2021